Fig. 5

(a) In the presence of ASCs and a fibrin hydrogel system, LECs (green) and BECs (red) form networks that are distinct from each other. With the supplementation of VEGF-C, LECs form denser networks. Scale bars are 100μm. Illustration in panel A was adapted with permission from [201]. (b) With the addition of interstitial flow to the culture chamber, LECs formed capillaries after five days of continuous flow. Confocal imaging shows the multicellular networks(ii) and confocal reflectance indicates the networks contain lumens (iii). Illustration in panel B was adapted with permission from [231]