Fig. 3
From: Quest for cardiovascular interventions: precise modeling and 3D printing of heart valves
Schematic representation of the proposed process for the generation of 3D heart valves through combining either bioprinting or combination of 3D printing and electrospinning with bioreactor to arrive at functional tissue engineered heart valves (a) slice of CT images, (b)3D CAD model generation, (c) 3D bioprinting through bioink/ 3D printing through PLA, PCL materials, (d) combining PCL-Gel electrospun nanofibrous with 3D printed scaffold, (e) scaffold ready for conventional tissue engineering (f) Development of tissue through combining stem cells, growth factors and developed scaffold, (g) Development and initial tissue remodeling in perfusion bioreactor under dynamic pulsatile flow conditions