Fig. 2
From: Development of a novel heterologous β-lactam-specific whole-cell biosensor in Bacillus subtilis
Minimal inhibitory concentrations [4] for B. subtilis strains. The MICs for the B. subtilis wild type and strains missing either ybxI (TMB3668), penP (TMB3667) or both genes (TMB3675) coding for potential β-lactamases are shown. The x-axis indicates the concentration of each antimicrobial compound added to the different strains. Note that the concentration range varies depending on the antibiotic tested due to different susceptibilities. The y-axis shows the growth of the cultures displayed as OD600nm. Displayed are representative examples of the four β-lactam classes: penicillin G, ampicillin and carbenicillin (penicillins), cefoperazone (cephalosporins), aztreonam (monobactams) and meropenem (carbapenems). For the full dataset, see Supplement 1, Figure S4