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Fig. 9 | Journal of Biological Engineering

Fig. 9

From: Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting

Fig. 9

Release and cytotoxicity assessment of EPI using EPI & AG-G5 nanogels as a pH-responsive carrier. a Schematic representation of EPI & AG-G5 nanogels synthesis. b Time-dependent cumulative release profiles of EPI from nanogels at two pH 7.4 and 5.5. c viability assessment of MCF-7 cells after 48 h incubation with the appropriate amount of nanogels equivalent to EPI concentrations. Statistical significance was carried out by Two-way ANOVA with Tukey’s multiple comparisons test between groups using GraphPad Prism 6.0 software. Statistically significant values were denoted by * (p < 0.05), ** (p < 0.005), and *** (p < 0.001). Statistically insignificant values were represented by ‘ns’ [101]. Matai, I. and P. Gopinath, Chemically cross-linked hybrid nanogels of alginate and PAMAM dendrimers as efficient anticancer drug delivery vehicles. ACS Biomaterials Science & Engineering. 2016, 2(2):213–223. Copyright (2020)

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Journal of Biological Engineering

ISSN: 1754-1611