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Fig. 2 | Journal of Biological Engineering

Fig. 2

From: Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation

Fig. 2

A representation of the multiscale process that governs mesangial expansion from the molecular level (yellow) to the cellular level (orange) and tissue level (blue). Interactions between these different scales are important, especially the feedback influence of changes in mesangial matrix structure, composition, and stiffness on mesangial cell behavior. Ang II: angiotensin II, HG: hyperglycemia

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Journal of Biological Engineering

ISSN: 1754-1611