Fig. 2
From: CD146 expression profile in human skin and pre-vascularized dermo-epidermal skin substitutes in vivo
Lymphatic capillaries are negative for CD146 expression. A, B, C Lymphatic and blood capillaries are discriminated as CD31 and Podoplanin/Lyve1/Prox1 double positive and CD31 positive Podoplanin/Lyve1/Prox1 negative, respectively. Representative immunofluorescence images show no expression of CD146 on lymphatic capillaries positive for Lyve1 (A), Podoplanin (B) and Prox1 (C, inset). CD146 expression is detected only on blood capillaries and their related perivascular cells. (n = 3 independent donors). Scale bar: 50 µm. White dashed lines indicate the epidermal-dermal junction