From: Therapeutic angiogenesis and tissue revascularization in ischemic vascular disease
First author | Phase year | Disease | Treatment | Subject(n) treatment/control | Findings | Ref |
---|---|---|---|---|---|---|
Frey, N | Phase II 2014 | CHD | Intracoronary delivery of an innovative, injectable bioabsorbable scaffold (IK-5001) | 27/0 | Proven feasibility and good tolerability | [146] |
Florian, A | Phase II 2014 | CHD | Intravenous iron-oxide administration | 17/22 | Improved infarct healing and a beneficial global left ventricular remodeling | [123] |
Svystonyuk, D.A | Phase I 2020 | CHD | Intramyocardial grafting collagen scaffold with HUCMSC | 35/15 | Proven safety and efficacy | [138] |
Matsumoto, T | Phase I/IIa 2022 | CLI | Intramuscular pitavastatin-incorporated nanoparticles | 16/0 | Proven safety and efficacy | [131] |