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Fig. 2 | Journal of Biological Engineering

Fig. 2

From: The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition

Fig. 2

Analysis of ELF3 levels during induction of EMT and/or MET. A Scatterplot of ssGSEA scores for the “Hallmark EMT” pathway with ELF3 expression levels at different time points of EMT induction (GSE17708). Spearman’s correlation coefficient and corresponding p-value is given. B Scatterplot and trajectory of samples in terms of ssGSEA scores of Hallmark EMT with ELF3 expression in EMT induction via SNAIL over expression (5 days) and subsequent induction of MET over a 20-day period (GSE80042). C Same as B) but for treatment with TGFβ (red, orange profiles) and SNAIL induction (blue profile) over a 6-day time period (GSE89152). D Single-cell data of ELF3 levels in TGFβ treated A549 (left), DU145 (center) and OVCA420 (right) over a 7 day period (EMT) followed by TGFβ withdrawal (MET) for the next 3 days (GSE147405)

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