Table 3 Evaluation of parameters of various structural recognition properties of selected mAbs obtained by MS combination
Clone Name | KD (nM) | Hybridoma | BCR | H-LI per unit BCR | ||
|---|---|---|---|---|---|---|
H-LI (RFU) | Hybridoma Group | B-LI (RFU) | (H-LI)/(B-LI) | Group | ||
S2G3 | 14.2 | 60.86 | lH | 196.84 | 0.31 | hU |
S1H5 | 42.7 | 33.84 | lH | 225.39 | 0.15 | lU |
S2E3 | 57.7 | 114.50 | hH | 354.01 | 0.32 | hU |
S2H12 | 65.7 | 188.15 | hH | 424.08 | 0.44 | hU |
S2H5 | 71.0 | 44.37 | lH | 143.50 | 0.31 | hU |
S2E9 | 74.1 | 114.50 | hH | 405.36 | 0.28 | hU |
S1E1 | 132 | 46.42 | lH | 1046.18 | 0.04 | lU |
S2D10 | 136 | 69.68 | lH | 246.69 | 0.28 | hU |
S1B11 | 156 | 76.27 | lH | 188.15 | 0.41 | hU |
S2D7 | 204 | 179.85 | hH | 1046.18 | 0.17 | lU |
S2H9 | 213 | 95.59 | lH | 636.68 | 0.15 | lU |
S2F1 | 639 | 171.91 | hH | 1570.65 | 0.11 | lU |
S2E8 | 711 | 50.80 | lH | 729.03 | 0.07 | lU |
S1F3 | 815 | 100.00 | hH | 1145.05 | 0.09 | lU |
S1B8 | 821 | 157.06 | hH | 1253.25 | 0.13 | lU |