Fig. 4
From: Novel organoid construction strategy for non-involuting congenital hemangioma for drug validation
Transcriptome results of NICH organoids, NICH tissue and para-NICH tissue. (A) PCA of NICH PDOs (A1, A2, A3), NICH tissue (B1, B2, B3), and para-NICH tissue (C1, C2). Heatmap analysis of (B) NICH tissue with para-NICH tissue. (C) NICH PODs with para-NICH tissue. (D) NICH tissue with NICH PDOs. Volcano map of differentially expressed genes (log2FC > 1 and P-adjusted < 0.05 as a significant difference). Red dots indicate significantly upregulated genes, blue dots indicate significantly downregulated genes, and gray dots indicate nonsignificant genes. (E) NICH tissue compared with para-NICH tissue. (F) NICH PDOs compared with para-NICH tissue. (G) NICH organoid compared with NICH tissue