Fig. 2From: Comparative transcriptome findings reveal the neuroinflammatory network and potential biomarkers to early detection of ischemic strokeDifferentially expressed genes are involved in biological processes related to oxygen regulation, metabolism, cell signaling, and inflammation in the middle cerebral artery occlusion (MCAO) model. A The volcano plot showed the differential gene expression in the brain tissue of the MCAO model. The X-axis represents the fold change of the difference MCAO and control group after conversion to log 2, and the Y-axis represents the significance q-value after conversion to -log 10. Red dots represent upregulated genes, green dots represent downregulated genes, and grey dots represent non-changed genes. Gene ontology enrichment analysis highlighted the involvement of the differentially expressed genes in B oxygen regulation, C metabolism, D cell signaling, E inflammatory and immune responses, F cell proliferation, and apoptosis, and G neurological functions. The size of the dots represents the number of genes, and the color of the dots represents the significance of the processesBack to article page