Fig. 10
From: Optimizing the fabrication of a 3D high-resolution implant for neural stimulation
Histology of a flat mount retina implanted with the retinal device. a) Confocal imaging of the implanted retinal device (arrow) showing good anatomical integration in the subretinal space; scale bar = 100µm. The insert shows a high magnification of the micro-wells in the demarcated area showing proximity between the electrodes and bipolar cells entering the micro-wells; scale bar = 100µm. b) A cross section of the implanted retina showing the proximity between the implant and the BPC layer with some of the cells migrating towards the micro-wells (arrows). c) A cross-section at the micro-wells’ mid-height (reference point: the white dashed line in b) revealing the presence of bipolar cells within the micro-wells. Scale bar = 50µm. GC—ganglion cells, BPC—bipolar cells. Green—PKCα, blue—Nuclei