Fig. 5

Effect of various coatings on cell adhesion to gold electrodes. a-b) SEM image of ARPE cells seeded on gold electrodes (40 µm in diameter, white arrows), used to quantify the effect of various coatings on cell adhesion and the preference of gold electrodes without RGD (a) and with RGD (b); the scale bar = 200 µm. It can clearly be seen that although the cells tend to be repelled by bare gold electrodes (a), the cells tend to adhere to RGD-coated gold electrodes (b). c) The obtained adhesion of cells to gold electrodes for the various coatings defined as the prevention of the electrode area occupied by cells divided by the percentage of the area surrounding the electrodes occupied by cells. Values larger than the one obtained for the RGD coating reveal the cell’s preference for electrodes following this treatment, compared to the control