Fig. 8
A Flowcytometric analysis of HT-29 cells after treatment with IC50 concentration of PX-12, YC-1, YC/PX, NIO/YC-PX, and free noisome. Lower left panel (Q4): live cells, upper left panel (Q1): necrosis, lower right panel (Q3): early apoptosis, upper right panel (Q2): late apoptosis. B-C Early and late apoptosis and necrosis of HT-29 cells treated with pX-12, YC-1, YC/PX, NIO/YC-PX, and Blank niosome after 24 and 48 h, respectively. All tests were repeated three times and the data are shown based on (mean ± SD). *p < 0.05, **p < 0.01, and ***p < 0.001