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Table 1 Different levels for variables in the CCD optimizationa

From: Efficient targeting of HIF-1α mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy

Level

-1

0

 + 1

A (Lipid content, µmol)

200

250

300

B (Surfactant: Cholesterol, molar ratio)

0.5

1

2

  1. aSonication time:5 min; Span60:Tween60 = 1:1