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Table 5 The optimized responses obtained by the CCD method and the experimental data for the same responses under the optimum conditions

From: Efficient targeting of HIF-1α mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy

Parameter

Predicted by Box-Behnken

Experimental Data

Average size (nm)

197.372

185.00 ± 5.40

PDI

0.188

0.179 ± 0.012

Entrapment Efficiency (EEPX) (%)

92.141

91.24 ± 1.15

Entrapment Efficiency (EEYC) (%)

75.410

78.36 ± 1.54