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Table 2 Surface modified biomimetic materials applied in implants

From: Research progress of biomimetic materials in oral medicine

biomimetic inspiration

Property

Material(s)

Category

Major Upside(s)

Major downside(s)

Reference

fish scales surface

super-hydrophilicity

PEG

polymers

Anti-fouling, bacteriostasis, after adding cell adhesive sequences, it has favorable biocompatibility and bone binding

A risk of polymer degradation with time

[162]

AMP

peptides

Anti-fouling, bactericidal capability, low cellular cytotoxicity, low antibiotic resistance

Structural complexity, expensive

[163]

lotus leaf surface

super-hydrophobicity

Silane

Silicon based materials

Bactericidal capability, osseointegration performance

—

[164]

Wing-shaped nanopillar structure of Cicada or dragonfly

bactericidal capability, self-cleaning property

Ti

metal

Bactericidal capability (S. epidermidis), hydrophobicity, low antibiotic resistance

—

[165]

TiO2

metal

Higher bactericidal capability (E. coli and S. aureus)

—

[166]

ZnO

metal

Bactericidal capability (E. coli and S. aureus)

—

[167]

FHA

Ceramic

Bactericidal capability, hydrophilic, good osseointegration

—

[168]

bSi

Silicon substrate

Highly hydrophobic, bactericidal capability (P. aeruginosa and S. aureus)

Sterilization was less effective than previously reported

[169]

SiO2

Silicon substrate

Higher bactericidal capability efficiency

—

[170]

PET

polymer

Bactericidal capability (E. coli and Klebsiella pneumoniae)

—

[171]

PS-block-PMMA

copolymer

Dual bactericidal and bacteria-releasing function

—

[172]

ZnO-PSBMA

Composite material

Dual bactericidal and bacteria-releasing function

—

[173]

  1. Abbreviations: PEG polyethylene glycol, AMP antimicrobial peptide, FHA fluoridated hydroxyapatite, bSi black silicon, PET polyethylene terephthalate, PS-block-PMMA polystyrene-block-polymethy lmethacrylate, ZnO-PSBMA ZnO-poly sulfobetaine methacrylate