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Table 2 Advantages and disadvantages of chitosan nanoparticles

From: Chitosan as a promising materials for the construction of nanocarriers for diabetic retinopathy: an updated review

Advantages of nanoparticles of chitosan

Disadvantages of nanoparticles of chitosan

Less toxic

Possible contraction

Improve biocompatibility

Less mechanical resistance

Muco-adhesiveness

Low solubility in alkaline and neutral pH

Targeted drug delivery

Difficult pore size control

Stability

Effect of cross-linking on chitosan

Increase therapeutic efficacy

Problem in electrospinning