Fig. 14.
From: Promoting osteogenesis and bone regeneration employing icariin-loaded nanoplatforms
A Photographs illustrating the surgical implantation procedure of CPH and CPHI scaffolds in rabbit bone defects (A1 and A2). Additionally, (A3) shows the defect control group covered by connective tissue after 12 weeks. B The progression of new bone formation in the CPH and CPHI groups over 4, 8, and 12 weeks (B1-B6). C Present representative X-ray images evaluating the level of regenerated bone tissue after 4-12 weeks (C1-C9). D reconstruction images revealed the distinct reparative effects of the CPH and CPHI scaffolds after 4-12 weeks (D1-D9). Red arrows indicate bone density, red dotted circles highlight defect areas, and red arrows denote areas of dense bone regeneration. Reprinted with permission from [160]