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Research
With additive manufacturing (AM) individual and biocompatible implants can be generated by using suitable materials. The aim of this study was to investigate the biological effects of polylactic acid (PLA) man...
Journal of Biological Engineering 2017 11:29
Published on: 12 September 2017
Research
Plasmid-borne genetic editing tools, including the widely used CRISPR-Cas9 system, have greatly facilitated bacterial programming to obtain novel functionalities. However, the lack of effective post-editing pl...
Journal of Biological Engineering 2017 11:32
Published on: 4 September 2017
Review
Due to steadily growing population and economic transitions in the more populous countries, renewable sources of energy are needed more than ever. Plant biomass as a raw source of bioenergy and biofuel product...
Journal of Biological Engineering 2017 11:27
Published on: 1 September 2017
Research
In the yeast Saccharomyces cerevisiae, as in every eukaryotic organism, the mRNA 5′-untranslated region (UTR) is important for translation initiation. However, the patterns and mechanisms that determine the effic...
Journal of Biological Engineering 2017 11:25
Published on: 21 August 2017
Research
The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a...
Journal of Biological Engineering 2017 11:24
Published on: 3 August 2017
Research
Biotechnological development in shake flask necessitates vital engineering parameters e.g. volumetric power input, mixing time, gas liquid mass transfer coefficient, hydromechanical stress and effective shear ...
Journal of Biological Engineering 2017 11:28
Published on: 3 August 2017
Research
The configuration of necrotic areas within the retinal pigmented epithelium is an important element in the progression of age-related macular degeneration (AMD). In the exudative (wet) and non-exudative (dry) ...
Journal of Biological Engineering 2017 11:26
Published on: 2 August 2017
Research
Poly(γ-glutamic acid) (γ-PGA) is a biopolymer with many useful properties making it applicable for instance in food and skin care industries, in wastewater treatment, in biodegradable plastics or in the pharma...
Journal of Biological Engineering 2017 11:23
Published on: 12 July 2017
Methodology
Escherichia coli is often used for recombinant protein production. The expression of recombinant proteins negatively affects the microbial growth, thus, a balance between protein expre...
Journal of Biological Engineering 2017 11:20
Published on: 3 July 2017
Review
Recent advances in the expansion and directed pancreatogenic differentiation of human pluripotent stem cells (hPSCs) have intensified efforts to generate functional pancreatic islet cells, especially insulin-s...
Journal of Biological Engineering 2017 11:21
Published on: 3 July 2017
Review
In situ tissue regeneration approach aims to exploit the body’s own biological resources and reparative capability and recruit host cells by utilizing cell-instructive biomaterials. In or...
Journal of Biological Engineering 2017 11:22
Published on: 29 June 2017
Research
Synechococcus sp. PCC 7002 (henceforth Synechococcus) is developing into a powerful synthetic biology chassis. In order to streamline the integration of genes into the Synechococcus ch...
Journal of Biological Engineering 2017 11:19
Published on: 5 June 2017
Research
High-throughput methods based on molecular reporters have greatly advanced our knowledge of cell signaling in mammalian cells. However, their ability to monitor various types of cells is markedly limited by th...
Journal of Biological Engineering 2017 11:18
Published on: 5 June 2017
Research
Probiotic bacteria are becoming an important tool for improving human health, controlling diseases and enhancing immune responses. The availability of a cost effective cultivation conditions has profound effec...
Journal of Biological Engineering 2017 11:17
Published on: 5 May 2017
Review
Two important and large non-point sources of nitrogen in residential areas that adversely affect water quality are stormwater runoff and effluent from on-site treatment systems. These sources are challenging t...
Journal of Biological Engineering 2017 11:16
Published on: 1 May 2017
Research
Umbelliferone, also known as 7-hydroxycoumarin, is a phenolic metabolite found in many familiar plants. Its derivatives have been shown to have various pharmacological and chemo-preventive effects on human hea...
Journal of Biological Engineering 2017 11:15
Published on: 5 April 2017
Research
Physical scaffolds are useful for supporting cells to form three-dimensional (3D) tissue. However, it is non-trivial to develop a scheme that can robustly guide cells to self-organize into a tissue with the de...
Journal of Biological Engineering 2017 11:12
Published on: 3 April 2017
Research
Nuclear magnetic resonance (NMR) technique is a powerful analytical tool in determining the presence of bacterial contaminants in complex biological samples. In this paper, a portable NMR-based (pNMR) biosenso...
Journal of Biological Engineering 2017 11:14
Published on: 27 March 2017
Review
Nanomedicine has seen a significant increase in research on stimuli-responsive activatable nanoprobes for tumor-specific delivery and diagnosis. The tumor microenvironment has particular characteristics that c...
Journal of Biological Engineering 2017 11:13
Published on: 23 March 2017
Review
Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detectio...
Journal of Biological Engineering 2017 11:11
Published on: 13 March 2017
Review
Prototypical abnormalities of genome-wide DNA methylation constitute the most widely investigated epigenetic mechanism in human cancers. Errors in the cellular machinery to faithfully replicate the global 5-me...
Journal of Biological Engineering 2017 11:10
Published on: 1 March 2017
Methodology
Quantifying gene expression at single cell level is fundamental for the complete characterization of synthetic gene circuits, due to the significant impact of noise and inter-cellular variability on the system...
Journal of Biological Engineering 2017 11:8
Published on: 20 February 2017
Research
It is challenging to achieve ultrasensitive and selective detection of waterborne pathogens at extremely low levels (i.e., single cell/mL) using conventional methods. Even with molecular methods such as ELISA ...
Journal of Biological Engineering 2017 11:9
Published on: 14 February 2017
Research
Deposits of aggregated amyloid-β protein (Aβ) are a pathological hallmark of Alzheimer’s disease (AD). Thus, one therapeutic strategy is to eliminate these deposits by halting Aβ aggregation. While a variety o...
Journal of Biological Engineering 2017 11:5
Published on: 6 February 2017
Research
During hydrous ethanol production from the sugar refinery industry in Mexico, vinasse is generated. Phenolic compounds and melanoidins contribute to its color and make degradation of the vinasse a difficult ta...
Journal of Biological Engineering 2017 11:6
Published on: 23 January 2017
