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  1. Efflux pump activity has been associated with multidrug resistance phenotypes in bacteria, compromising the effectiveness of antimicrobial therapy. The development of methods for the early detection and quanti...

    Authors: Laura Paixão, Liliana Rodrigues, Isabel Couto, Marta Martins, Pedro Fernandes, Carla CCR de Carvalho, Gabriel A Monteiro, Filipe Sansonetty, Leonard Amaral and Miguel Viveiros
    Citation: Journal of Biological Engineering 2009 3:18
  2. Cnidocysts isolated from cnidarian organisms are attractive as a drug-delivery platform due to their fast, efficient delivery of toxins. The cnidocyst could be utilized as the means to deliver therapeutics in ...

    Authors: Shawn C Oppegard, Peter A Anderson and David T Eddington
    Citation: Journal of Biological Engineering 2009 3:17
  3. Biological engineering will play a significant role in solving many of the world's problems in medicine, agriculture, and the environment. Recently the U.S. National Academy of Engineering (NAE) released a doc...

    Authors: Jeong-Yeol Yoon and Mark R Riley
    Citation: Journal of Biological Engineering 2009 3:16
  4. Advances in synthetic biology will require spatio-temporal regulation of biological processes in heterologous host cells. We develop a light-switchable, two-hybrid interaction in yeast, based upon the Arabidop...

    Authors: Oxana Sorokina, Anita Kapus, Kata Terecskei, Laura E Dixon, Laszlo Kozma-Bognar, Ferenc Nagy and Andrew J Millar
    Citation: Journal of Biological Engineering 2009 3:15
  5. Determination of lipophilicity as a tool for predicting pharmacokinetic molecular behavior is limited by the predictive power of available experimental models of the biomembrane. There is current interest, the...

    Authors: Sunday Olakunle Idowu, Morenikeji Ambali Adeyemo and Udochi Ihechiluru Ogbonna
    Citation: Journal of Biological Engineering 2009 3:14
  6. Escherichia coli exhibits diauxic growth in sugar mixtures due to CRP-mediated catabolite repression and inducer exclusion related to phosphotransferase system enzyme activity. Replacement of the native crp gene ...

    Authors: Reza Khankal, Jonathan W Chin, Debashis Ghosh and Patrick C Cirino
    Citation: Journal of Biological Engineering 2009 3:13
  7. Bacterial cellulose has been used in the food industry for applications such as low-calorie desserts, salads, and fabricated foods. It has also been used in the paper manufacturing industry to enhance paper st...

    Authors: Kuan-Chen Cheng, Jeff M Catchmark and Ali Demirci
    Citation: Journal of Biological Engineering 2009 3:12
  8. The Hamiltonian Path Problem asks whether there is a route in a directed graph from a beginning node to an ending node, visiting each node exactly once. The Hamiltonian Path Problem is NP complete, achieving s...

    Authors: Jordan Baumgardner, Karen Acker, Oyinade Adefuye, Samuel Thomas Crowley, Will DeLoache, James O Dickson, Lane Heard, Andrew T Martens, Nickolaus Morton, Michelle Ritter, Amber Shoecraft, Jessica Treece, Matthew Unzicker, Amanda Valencia, Mike Waters, AMalcolm Campbell…
    Citation: Journal of Biological Engineering 2009 3:11
  9. Gradients of morphogens pattern cell fate – a phenomenon that is especially important during development. A simple model system for studying how morphogens pattern cell behavior would overcome difficulties inh...

    Authors: Takayuki Sohka, Richard A Heins and Marc Ostermeier
    Citation: Journal of Biological Engineering 2009 3:10
  10. The release of heavy metal-containing nanoparticles (NP) into the environment may be harmful to the efficacy of beneficial microbes that function in element cycling, pollutant degradation and plant growth. Nan...

    Authors: Priyanka Gajjar, Brian Pettee, David W Britt, Wenjie Huang, William P Johnson and Anne J Anderson
    Citation: Journal of Biological Engineering 2009 3:9
  11. The following essay was written by a sophomore undergraduate student majoring in Bioengineering at the University of Maryland, Mr. Zachary Russ. Mr. Russ was one of 174 students who submitted a 1000–1200 word ...

    Authors: Zachary N Russ
    Citation: Journal of Biological Engineering 2009 3:7
  12. Self-assembly of the amyloid-β peptide (Aβ) has been implicated in the pathogenesis of Alzheimer's disease (AD). As a result, synthetic molecules capable of inhibiting Aβ self-assembly could serve as therapeut...

    Authors: Adriana A Reyes Barcelo, Francisco J Gonzalez-Velasquez and Melissa A Moss
    Citation: Journal of Biological Engineering 2009 3:5
  13. The engineering of many-component, synthetic biological systems is being made easier by the development of collections of reusable, standard biological parts. However, the complexity of biology makes it diffic...

    Authors: Jason R Kelly, Adam J Rubin, Joseph H Davis, Caroline M Ajo-Franklin, John Cumbers, Michael J Czar, Kim de Mora, Aaron L Glieberman, Dileep D Monie and Drew Endy
    Citation: Journal of Biological Engineering 2009 3:4
  14. Apple juice prepared from 'Annurca' apple puree was treated with a HPCD batch system. The pH, °Brix, color parameters and microbial load of the treated apple juice were compared with those of thermally process...

    Authors: Giovanna Ferrentino, Mariacarmela Bruno, Giovanna Ferrari, Massimo Poletto and Murat O Balaban
    Citation: Journal of Biological Engineering 2009 3:3
  15. The current knowledge of genes and proteins comes from 'naturally designed' coding and non-coding regions. It would be interesting to move beyond natural boundaries and make user-defined parts. To explore this...

    Authors: Pawan K Dhar, Chaw Su Thwin, Kyaw Tun, Yuko Tsumoto, Sebastian Maurer-Stroh, Frank Eisenhaber and Uttam Surana
    Citation: Journal of Biological Engineering 2009 3:2
  16. Microbial communities are involved in many processes relevant to industrial and medical biotechnology, such as the formation of biofilms, lignocellulosic degradation, and hydrogen production. The manipulation ...

    Authors: Travis S Bayer, Kevin G Hoff, Chase L Beisel, Jack J Lee and Christina D Smolke
    Citation: Journal of Biological Engineering 2009 3:1
  17. Immediately after damage to the nervous system, a cascade of physical, physiological, and anatomical events lead to the collapse of neuronal function and often death. This progression of injury processes is ca...

    Authors: Mahvash Zuberi, Peishan Liu-Snyder, Aeraj ul Haque, David M Porterfield and Richard B Borgens
    Citation: Journal of Biological Engineering 2008 2:17
  18. Vibrational spectroscopic techniques are becoming increasingly important and popular because they have the potential to provide rapid and convenient solutions to routine analytical problems. Using these techni...

    Authors: Frank Leitermann, Christoph Syldatk and Rudolf Hausmann
    Citation: Journal of Biological Engineering 2008 2:13
  19. Human solid tumors that are hard or firm on physical palpation are likely to be cancerous, a clinical maxim that has been successfully applied to cancer screening programs, such as breast self-examination. How...

    Authors: Nagesh Ragavendra, JW Ju, James W Sayre, Sharon Hirschowitz, Inder Chopra and Michael W Yeh
    Citation: Journal of Biological Engineering 2008 2:12
  20. Humic acid (HA) has been found to affect the solubility, mineralization, and bound residue formation of polycyclic aromatic hydrocarbons (PAHs). However, most of the studies on the interaction between HA and P...

    Authors: Yanna Liang, Darwin L Sorensen, Joan E McLean and Ronald C Sims
    Citation: Journal of Biological Engineering 2008 2:11
  21. Glucagon is a peptide hormone with many uses as a therapeutic agent, including the emergency treatment of hypoglycemia. Physical instability of glucagon in solution leads to problems with the manufacture, form...

    Authors: Cindy C Hoppe, Lida T Nguyen, Lee E Kirsch and John M Wiencek
    Citation: Journal of Biological Engineering 2008 2:10
  22. Polyethylene glycol (PEG; 2000 MW, 30% by volume) has been shown to mechanically repair damaged cellular membranes and reduce secondary axotomy after traumatic brain and spinal cord injury (TBI and SCI respect...

    Authors: Andrew O Koob, Julia M Colby and Richard B Borgens
    Citation: Journal of Biological Engineering 2008 2:9
  23. We investigated the possibility of executing DNA-based computation in living cells by engineering Escherichia coli to address a classic mathematical puzzle called the Burnt Pancake Problem (BPP). The BPP is solve...

    Authors: Karmella A Haynes, Marian L Broderick, Adam D Brown, Trevor L Butner, James O Dickson, W Lance Harden, Lane H Heard, Eric L Jessen, Kelly J Malloy, Brad J Ogden, Sabriya Rosemond, Samantha Simpson, Erin Zwack, A Malcolm Campbell, Todd T Eckdahl, Laurie J Heyer…
    Citation: Journal of Biological Engineering 2008 2:8
  24. The following essay was written by a freshman undergraduate student majoring in Bioengineering at the University of Maryland, Mr. Zachary Russ. Mr. Russ was one of 94 students who submitted a 1000 to 1200 word...

    Authors: Zachary N Russ
    Citation: Journal of Biological Engineering 2008 2:7
  25. Dielectrophoresis (DEP) has been regarded as a useful tool for manipulating biological cells prior to the detection of cells. Since DEP uses high AC electrical fields, it is important to examine whether these ...

    Authors: Liju Yang, Padmapriya P Banada, Arun K Bhunia and Rashid Bashir
    Citation: Journal of Biological Engineering 2008 2:6
  26. The underlying goal of synthetic biology is to make the process of engineering biological systems easier. Recent work has focused on defining and developing standard biological parts. The technical standard th...

    Authors: Reshma P Shetty, Drew Endy and Thomas F Knight Jr
    Citation: Journal of Biological Engineering 2008 2:5
  27. Although the production of poly-β-hydroxybutyrate (PHB) has many biological, energetic and environmental advantages over chemically synthesized polymers, synthetic polymers continue to be produced industrially si...

    Authors: Pratap R Patnaik
    Citation: Journal of Biological Engineering 2008 2:4
  28. We report a new approach for the simultaneous conversion of xylose and glucose sugar mixtures into products by fermentation. The process simultaneously uses two substrate-selective strains of Escherichia coli, on...

    Authors: Mark A Eiteman, Sarah A Lee and Elliot Altman
    Citation: Journal of Biological Engineering 2008 2:3
  29. Feed-forward motifs are important functional modules in biological and other complex networks. The functionality of feed-forward motifs and other network motifs is largely dictated by the connectivity of the i...

    Authors: Advait A Apte, John W Cain, Danail G Bonchev and Stephen S Fong
    Citation: Journal of Biological Engineering 2008 2:2
  30. Value-added processing with respect to rice milling has traditionally treated the rice bran layer as a homogenous material that contains significant concentrations of high-value components of interest for phar...

    Authors: Rebecca Schramm, Alicia Abadie, Na Hua, Zhimin Xu and Marybeth Lima
    Citation: Journal of Biological Engineering 2007 1:9
  31. Synthetic biology is an emerging engineering discipline that, if successful, will allow well-characterized biological components to be predictably and reliably built into robust organisms that achieve specific...

    Authors: Natalie Kuldell
    Citation: Journal of Biological Engineering 2007 1:8
  32. Living through hurricane Katrina and its aftermath and reflecting on these experiences from technical and non-technical standpoints has led me to reconsider my thoughts and philosophy on engineering education....

    Authors: Marybeth Lima
    Citation: Journal of Biological Engineering 2007 1:6
  33. The use of nanopillar array electrodes (NAEs) for biosensor applications was explored using a combined experimental and simulation approach to characterize the role of reaction kinetics and mass transport in g...

    Authors: Venkataramani Anandan, Xiaoling Yang, Euihyeon Kim, Yeswanth L Rao and Guigen Zhang
    Citation: Journal of Biological Engineering 2007 1:5
  34. Efficient functioning of enzymes inside liposomes would open new avenues for applications in biocatalysis and bioanalytical tools. In this study, the entrapment of amyloglucosidase (AMG) (EC 3.2.1.3) from Aspergi...

    Authors: Mian Li, Michael J Hanford, Jin-Woo Kim and Tonya L Peeples
    Citation: Journal of Biological Engineering 2007 1:4
  35. An intestinal protozoan parasite, Cryptosporidium parvum, is a major cause of waterborne gastrointestinal disease worldwide. Detection of Cryptosporidium oocysts in potable water is a high priority for the water ...

    Authors: Marianne F Kramer, Graham Vesey, Natasha L Look, Ben R Herbert, Joyce M Simpson-Stroot and Daniel V Lim
    Citation: Journal of Biological Engineering 2007 1:3
  36. Electrospinning is a non-mechanical processing strategy that can be used to process a variety of native and synthetic polymers into highly porous materials composed of nano-scale to micron-scale diameter fiber...

    Authors: Ashley E Manis, James R Bowman, Gary L Bowlin and David G Simpson
    Citation: Journal of Biological Engineering 2007 1:2