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Journal of Biological Engineering


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  1. Content type: Research

    In the yeast Saccharomyces cerevisiae, as in every eukaryotic organism, the mRNA 5-untranslated region (UTR) is important for translation initiation. However, the patterns and mechanisms that determine the effic...

    Authors: Jing Li, Qiang Liang, Wenjiang Song and Mario Andrea Marchisio

    Citation: Journal of Biological Engineering 2017 11:25

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  2. Content type: Research

    The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a...

    Authors: Markus J. Schmidt, David Sauter and Thomas Rösgen

    Citation: Journal of Biological Engineering 2017 11:24

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  3. Content type: Research

    The configuration of necrotic areas within the retinal pigmented epithelium is an important element in the progression of age-related macular degeneration (AMD). In the exudative (wet) and non-exudative (dry) ...

    Authors: Qanita Bani Baker, Gregory J. Podgorski, Elizabeth Vargis and Nicholas S. Flann

    Citation: Journal of Biological Engineering 2017 11:26

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  4. Content type: Research

    Poly(γ-glutamic acid) (γ-PGA) is a biopolymer with many useful properties making it applicable for instance in food and skin care industries, in wastewater treatment, in biodegradable plastics or in the pharma...

    Authors: Lena Regestein née Meissner, Julia Arndt, Thomas G. Palmen, Tim Jestel, Hitoshi Mitsunaga, Eiichiro Fukusaki and Jochen Büchs

    Citation: Journal of Biological Engineering 2017 11:23

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  5. Content type: Methodology

    Escherichia coli is often used for recombinant protein production. The expression of recombinant proteins negatively affects the microbial growth, thus, a balance between protein expre...

    Authors: Tobias Ladner, Martina Mühlmann, Andreas Schulte, Georg Wandrey and Jochen Büchs

    Citation: Journal of Biological Engineering 2017 11:20

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  6. Content type: Review

    Recent advances in the expansion and directed pancreatogenic differentiation of human pluripotent stem cells (hPSCs) have intensified efforts to generate functional pancreatic islet cells, especially insulin-s...

    Authors: Elena F. Jacobson and Emmanuel S. Tzanakakis

    Citation: Journal of Biological Engineering 2017 11:21

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  7. Content type: Research

    Synechococcus sp. PCC 7002 (henceforth Synechococcus) is developing into a powerful synthetic biology chassis. In order to streamline the integration of genes into the Synechococcus ch...

    Authors: Anne Ilse Maria Vogel, Rahmi Lale and Martin Frank Hohmann-Marriott

    Citation: Journal of Biological Engineering 2017 11:19

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  8. Content type: Research

    High-throughput methods based on molecular reporters have greatly advanced our knowledge of cell signaling in mammalian cells. However, their ability to monitor various types of cells is markedly limited by th...

    Authors: Zhiwen Zhang, Zachary Stickney, Natalie Duong, Kevin Curley and Biao Lu

    Citation: Journal of Biological Engineering 2017 11:18

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  9. Content type: Research

    Probiotic bacteria are becoming an important tool for improving human health, controlling diseases and enhancing immune responses. The availability of a cost effective cultivation conditions has profound effec...

    Authors: Asma Manzoor, Javed Iqbal Qazi, Ikram ul Haq, Hamid Mukhtar and Akhtar Rasool

    Citation: Journal of Biological Engineering 2017 11:17

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  10. Content type: Review

    Two important and large non-point sources of nitrogen in residential areas that adversely affect water quality are stormwater runoff and effluent from on-site treatment systems. These sources are challenging t...

    Authors: E. V. Lopez-Ponnada, T. J. Lynn, M. Peterson, S. J. Ergas and J. R. Mihelcic

    Citation: Journal of Biological Engineering 2017 11:16

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  11. Content type: Research

    Umbelliferone, also known as 7-hydroxycoumarin, is a phenolic metabolite found in many familiar plants. Its derivatives have been shown to have various pharmacological and chemo-preventive effects on human hea...

    Authors: Luan Luong Chu, Ramesh Prasad Pandey, Haet Nim Lim, Hye Jin Jung, Nguyen Huy Thuan, Tae-Su Kim and Jae Kyung Sohng

    Citation: Journal of Biological Engineering 2017 11:15

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  12. Content type: Research

    Physical scaffolds are useful for supporting cells to form three-dimensional (3D) tissue. However, it is non-trivial to develop a scheme that can robustly guide cells to self-organize into a tissue with the de...

    Authors: Xiaolu Zhu, Shiva Gojgini, Ting-Hsuan Chen, Peng Fei, Siyan Dong, Chih-Ming Ho and Tatiana Segura

    Citation: Journal of Biological Engineering 2017 11:12

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  13. Content type: Research

    Nuclear magnetic resonance (NMR) technique is a powerful analytical tool in determining the presence of bacterial contaminants in complex biological samples. In this paper, a portable NMR-based (pNMR) biosenso...

    Authors: Yilun Luo and Evangelyn C. Alocilja

    Citation: Journal of Biological Engineering 2017 11:14

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  14. Content type: Review

    Nanomedicine has seen a significant increase in research on stimuli-responsive activatable nanoprobes for tumor-specific delivery and diagnosis. The tumor microenvironment has particular characteristics that c...

    Authors: Byunghoon Kang, Aastha Kukreja, Daesub Song, Yong-Min Huh and Seungjoo Haam

    Citation: Journal of Biological Engineering 2017 11:13

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  15. Content type: Review

    Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detectio...

    Authors: Ho Bin Seo and Man Bock Gu

    Citation: Journal of Biological Engineering 2017 11:11

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  16. Content type: Methodology

    Quantifying gene expression at single cell level is fundamental for the complete characterization of synthetic gene circuits, due to the significant impact of noise and inter-cellular variability on the system...

    Authors: Marilisa Cortesi, Lucia Bandiera, Alice Pasini, Alessandro Bevilacqua, Alessandro Gherardi, Simone Furini and Emanuele Giordano

    Citation: Journal of Biological Engineering 2017 11:8

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  17. Content type: Research

    It is challenging to achieve ultrasensitive and selective detection of waterborne pathogens at extremely low levels (i.e., single cell/mL) using conventional methods. Even with molecular methods such as ELISA ...

    Authors: Chao Wang, Foram Madiyar, Chenxu Yu and Jun Li

    Citation: Journal of Biological Engineering 2017 11:9

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  18. Content type: Research

    Deposits of aggregated amyloid-β protein (Aβ) are a pathological hallmark of Alzheimer’s disease (AD). Thus, one therapeutic strategy is to eliminate these deposits by halting Aβ aggregation. While a variety o...

    Authors: Kelly A. Moore, Kayla M. Pate, Deborah D. Soto-Ortega, Samuel Lohse, Nicholas van der Munnik, Mihyun Lim, Kaliah S. Jackson, Venetia D. Lyles, Lemeisha Jones, Nisha Glassgow, Vanessa M. Napumecheno, Shanee Mobley, Mark J. Uline, Rahina Mahtab, Catherine J. Murphy and Melissa A. Moss

    Citation: Journal of Biological Engineering 2017 11:5

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  19. Content type: Research

    Microbial consortia composed of autotrophic and heterotrophic species abound in nature, yet examples of synthetic communities with mixed metabolism are limited in the laboratory. We previously engineered a mod...

    Authors: Stephanie G. Hays, Leo L. W. Yan, Pamela A. Silver and Daniel C. Ducat

    Citation: Journal of Biological Engineering 2017 11:4

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  20. Content type: Research

    During hydrous ethanol production from the sugar refinery industry in Mexico, vinasse is generated. Phenolic compounds and melanoidins contribute to its color and make degradation of the vinasse a difficult ta...

    Authors: Elda España-Gamboa, Teresa Vicent, Xavier Font, Jorge Dominguez-Maldonado, Blondy Canto-Canché and Liliana Alzate-Gaviria

    Citation: Journal of Biological Engineering 2017 11:6

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