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  1. Content type: Research

    Cellulases are key player in the hydrolyzation of cellulose. Unfortunately, this reaction is slow and a bottleneck in the process chain from biomass to intermediates and biofuels due to low activities of the e...

    Authors: Martina Mühlmann, Martin Kunze, Joaquim Ribeiro, Bertram Geinitz, Christian Lehmann, Ulrich Schwaneberg, Ulrich Commandeur and Jochen Büchs

    Citation: Journal of Biological Engineering 2017 11:1

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  2. Content type: Research

    Biofilm-based microalgal growth was determined as functions of organic chemical loading and water temperature utilizing dairy wastewater from a full-scale dairy farm. The dairy industry is a significant source...

    Authors: Zachary T. Fica and Ronald C. Sims

    Citation: Journal of Biological Engineering 2016 10:18

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  3. Content type: Review

    There have been many trials to visualize smell using various techniques in order to objectively express the smell because information obtained from the sense of smell in human is very subjective. So far, well-...

    Authors: Hwi Jin Ko and Tai Hyun Park

    Citation: Journal of Biological Engineering 2016 10:17

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  4. Content type: Review

    Each cell forever interacts with its extracellular matrix (ECM); a stem cell relies on this interaction to guide differentiation. The stiffness, nanotopography, protein composition, stress and strain inherent ...

    Authors: William J. Hadden and Yu Suk Choi

    Citation: Journal of Biological Engineering 2016 10:16

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  5. Content type: Research

    Cycles of covalent modification are ubiquitous motifs in cellular signalling. Although such signalling cycles are implemented via a highly concise set of chemical reactions, they have been shown to be capable ...

    Authors: Mathias Foo, Rucha Sawlekar and Declan G. Bates

    Citation: Journal of Biological Engineering 2016 10:15

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  6. Content type: Research

    Small-scale micro-bioreactors have become the cultivation vessel of choice during the first steps of bioprocess development. They combine high cultivation throughput with enhanced cost efficiency per cultivati...

    Authors: David Flitsch, Sebastian Krabbe, Tobias Ladner, Mario Beckers, Jana Schilling, Stefan Mahr, Uwe Conrath, Werner K. Schomburg and Jochen Büchs

    Citation: Journal of Biological Engineering 2016 10:14

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  7. Content type: Research

    Alkaline amylase has significant potential for applications in the textile, paper and detergent industries, however, low yield of which cannot meet the requirement of industrial application. In this work, a no...

    Authors: Yingfang Ma, Wei Shen, Xianzhong Chen, Long Liu, Zhemin Zhou, Fei Xu and Haiquan Yang

    Citation: Journal of Biological Engineering 2016 10:13

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  8. Content type: Research

    We propose, model, and implement a novel system of population-level intervention against a virus. One context is a treatment against a chronic infection such as HIV. The underlying principle is a form of virus...

    Authors: Matthew L. Paff, Scott L. Nuismer, Andrew D. Ellington, Ian J. Molineux, Ryan H. May and James J. Bull

    Citation: Journal of Biological Engineering 2016 10:12

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  9. Content type: Research

    Genetic code expansion has developed into an elegant tool to incorporate unnatural amino acids (uAA) at predefined sites in the protein backbone in response to an amber codon. However, recombinant production a...

    Authors: Georg Wandrey, Joel Wurzel, Kyra Hoffmann, Tobias Ladner, Jochen Büchs, Lorenz Meinel and Tessa Lühmann

    Citation: Journal of Biological Engineering 2016 10:11

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  10. Content type: Research

    The rapidly evolving discipline of biological and biomedical engineering requires adaptive instructional approaches that teach students to target and solve multi-pronged and ill-structured problems at the cutt...

    Authors: Ritu Raman, Marlon Mitchell, Pablo Perez-Pinera, Rashid Bashir and Lizanne DeStefano

    Citation: Journal of Biological Engineering 2016 10:10

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  11. Content type: Research

    In this study, a hybrid treatment system (Fluidized Bed positioned in a biological reactor of an Activated Sludge process) was used to treat saline domestic wastewater. The performance of the mentioned hybrid ...

    Authors: N. Salmanikhas, M. Tizghadam and A. Rashidi Mehrabadi

    Citation: Journal of Biological Engineering 2016 10:9

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  12. Content type: Research

    During the downstream process of bio-based bulk chemicals, organic impurities, mostly residues from the fermentation process, must be separated to obtain a pure and ready-to-market chemical. In this study, cap...

    Authors: Hendrik Laube, Frank-Michael Matysik, Andreas Schmidberger, Kerstin Mehlmann, Andreas Toursel and Jana Boden

    Citation: Journal of Biological Engineering 2016 10:7

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  13. Content type: Letter to the Editor

    CRISPR assisted homology directed repair enables the introduction of virtually any modification to the Saccharomyces cerevisiae genome. Of obvious interest is the marker-free and seamless introduction of point mu...

    Authors: Damien Biot-Pelletier and Vincent J. J. Martin

    Citation: Journal of Biological Engineering 2016 10:6

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  14. Content type: Research

    In recent years, there have been intensive efforts to develop synthetic microbial platforms for the production, biosensing and bio-remediation of fossil fuel constituents such as alkanes. Building predictable ...

    Authors: Toby P. Call, M. Kalim Akhtar, Frank Baganz and Chris Grant

    Citation: Journal of Biological Engineering 2016 10:5

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  15. Content type: Research

    Synthetic biology aims to engineer biological systems for desired behaviors. The construction of these systems can be complex, often requiring genetic reprogramming, extensive de novo DNA synthesis, and functi...

    Authors: Gregory Linshiz, Erik Jensen, Nina Stawski, Changhao Bi, Nick Elsbree, Hong Jiao, Jungkyu Kim, Richard Mathies, Jay D. Keasling and Nathan J. Hillson

    Citation: Journal of Biological Engineering 2016 10:3

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  16. Content type: Research

    Surface-enhanced Raman scattering (SERS) is a powerful light scattering technique that can be used for sensitive immunoassay development and cell labeling. A major obstacle to using SERS is the complexity of f...

    Authors: Nathan D. Israelsen, Donald Wooley, Cynthia Hanson and Elizabeth Vargis

    Citation: Journal of Biological Engineering 2016 10:2

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  17. Content type: Erratum

    Authors: Afnan Azizi, Wilson Lam, Hilary Phenix, Lioudmila Tepliakova, Ian J. Roney, Daniel Jedrysiak, Alex Power, Vaibhav Gupta, Nada Elnour, Martin Hanzel, Alexandra C. Tzahristos, Shihab Sarwar and Mads Kærn

    Citation: Journal of Biological Engineering 2016 10:1

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    The original article was published in Journal of Biological Engineering 2015 9:8

  18. Content type: Research

    Imbalances in gene expression of a metabolic pathway can result in less-yield of the desired products. Several targets were intensively investigated to balance the gene expression, such as promoter, ribosome b...

    Authors: Shasha Zhang, Xuejin Zhao, Yong Tao and Chunbo Lou

    Citation: Journal of Biological Engineering 2015 9:23

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  19. Content type: Research

    Plant terpenoids are known for their diversity, stereochemical complexity, and their commercial interest as pharmaceuticals, food additives, and cosmetics. Developing biotechnology approaches for the productio...

    Authors: Thiyagarajan Gnanasekaran, Konstantinos Vavitsas, Johan Andersen-Ranberg, Agnieszka Zygadlo Nielsen, Carl Erik Olsen, Björn Hamberger and Poul Erik Jensen

    Citation: Journal of Biological Engineering 2015 9:24

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  20. Content type: Research

    In the field of biomedical engineering, many studies have focused on the possible applications of graphene and related nanomaterials due to their potential for use as scaffolds, coating materials and delivery ...

    Authors: Yong Cheol Shin, Jong Ho Lee, Min Jeong Kim, Suck Won Hong, Bongju Kim, Jung Keun Hyun, Yu Suk Choi, Jong-Chul Park and Dong-Wook Han

    Citation: Journal of Biological Engineering 2015 9:22

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  21. Content type: Research

    Cell migration is a vital process for growth and repair. In vitro migration assays, utilized to study cell migration, often rely on physical scraping of a cell monolayer to induce cell migration. The physical act...

    Authors: Kaitlyn R. Ammann, Katrina J. DeCook, Phat L. Tran, Valerie M. Merkle, Pak K. Wong and Marvin J. Slepian

    Citation: Journal of Biological Engineering 2015 9:19

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  22. Content type: Research

    The interaction of stem cells with their culture substrates is critical in controlling their fate and function. Declining stemness of adult-derived human mesenchymal stem cells (hMSCs) during in vitro expansion o...

    Authors: Lucas H. Hofmeister, Lino Costa, Daniel A. Balikov, Spencer W. Crowder, Alexander Terekhov, Hak-Joon Sung and William H. Hofmeister

    Citation: Journal of Biological Engineering 2015 9:18

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  23. Content type: Letters to the Editor

    There is a general assent on the key role of standards in Synthetic Biology. In two consecutive letters to this journal, suggestions on the assembly methods for the Registry of standard biological parts have b...

    Authors: Cristina Vilanova, Kristie Tanner, Pedro Dorado-Morales, Paula Villaescusa, Divya Chugani, Alba Frías, Ernesto Segredo, Xavier Molero, Marco Fritschi, Lucas Morales, Daniel Ramón, Carlos Peña, Juli Peretó and Manuel Porcar

    Citation: Journal of Biological Engineering 2015 9:17

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  24. Content type: Methodology

    Molecular cloning is an essential step in biological engineering. Methods involving megaprimer-based PCR of a whole plasmid are promising alternatives to the traditional restriction-ligation-based molecular cl...

    Authors: Pawel Jajesniak and Tuck Seng Wong

    Citation: Journal of Biological Engineering 2015 9:15

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  25. Content type: Methodology

    Directing cell behaviour using controllable, on-demand non-biochemical methods, such as electrical stimulation is an attractive area of research. While there exists much potential in exploring different modes ...

    Authors: Gordon Minru Xiong, Anh Tuan Do, Jun Kit Wang, Chee Leong Yeoh, Kiat Seng Yeo and Cleo Choong

    Citation: Journal of Biological Engineering 2015 9:14

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  26. Content type: Research

    Extensive native Jatropha curcas L. (Jatropha) crop areas have been planted in Central America marginal lands since 2008 as a non-edible prospective feedstock alternative to high-value, edible palm oil. Jatropha ...

    Authors: Francisco Bueso, Luis Moreno, Mathew Cedeño and Karla Manzanarez

    Citation: Journal of Biological Engineering 2015 9:12

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  27. Content type: Methodology

    Chromosome engineering encompasses a collection of homologous recombination-based techniques that are employed to modify the genome of a model organism in a controlled fashion. Such techniques are widely used ...

    Authors: Sriram Tiruvadi Krishnan, M. Charl Moolman, Theo van Laar, Anne S. Meyer and Nynke H. Dekker

    Citation: Journal of Biological Engineering 2015 9:11

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  28. Content type: Letters to the Editor

    The Registry of Standard Biological Parts imposes sequence constraints to enable DNA assembly using restriction enzymes. Alnahhas et al. (Journal of Biological Engineering 2014, 8:28) recently argued that thes...

    Authors: Afnan Azizi, Wilson Lam, Hilary Phenix, Lioudmila Tepliakova, Ian J Roney, Daniel Jedrysiak, Alex Power, Vaibhav Gupta, Nada Elnour, Martin Hanzel, Alexandra C Tzahristos, Shihab Sarwar and Mads Kærn

    Citation: Journal of Biological Engineering 2015 9:8

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    The Erratum to this article has been published in Journal of Biological Engineering 2016 10:1

  29. Content type: Methodology

    We have developed a mixture of enzymes and chemicals that completely lyse cyanobacteria. Since the treatment involves only readily-available chemicals and simple proteins that degrade the components of the cya...

    Authors: Kunal K. Mehta, Niklaus H. Evitt and James R. Swartz

    Citation: Journal of Biological Engineering 2015 9:10

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  30. Content type: Research

    Conventional experiments in small scale are often performed in a ‘Black Box’ fashion, analyzing only the product concentration in the final sample. Online monitoring of relevant process characteristics and par...

    Authors: S. J. Wewetzer, M. Kunze, T. Ladner, B. Luchterhand, S. Roth, N. Rahmen, R. Kloß, A. Costa e Silva, L. Regestein and J. Büchs

    Citation: Journal of Biological Engineering 2015 9:9

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  31. Content type: Review

    3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D ...

    Authors: Helena N Chia and Benjamin M Wu

    Citation: Journal of Biological Engineering 2015 9:4

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  32. Content type: Research

    Unlike bone tissue, articular cartilage regeneration has not been very successful and has many challenges ahead. We have previously developed injectable hydrogels using photopolymerizable chitosan (MeGC) that ...

    Authors: Jinku Kim, Brian Lin, Soyon Kim, Bogyu Choi, Denis Evseenko and Min Lee

    Citation: Journal of Biological Engineering 2015 9:1

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  33. Content type: Research

    Cotton is an important domesticated fiber used to manufacture a variety of products and industrial goods. During harvesting with cotton strippers and cotton pickers, it is contaminated with foreign matter from...

    Authors: Adnan Mustafic, Changying Li and Mark Haidekker

    Citation: Journal of Biological Engineering 2014 8:29

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  34. Content type: Letters to Editor

    The Registry of Standard Biological Parts only accepts genetic parts compatible with the RFC 10 BioBrick format. This combined assembly and submission standard requires that four unique restriction enzyme site...

    Authors: Razan N Alnahhas, Ben Slater, Yunle Huang, Catherine Mortensen, Jordan W Monk, Yousef Okasheh, Marco D Howard, Neil R Gottel, Michael J Hammerling and Jeffrey E Barrick

    Citation: Journal of Biological Engineering 2014 8:28

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  35. Content type: Research

    In mammalian development, the formation of most tissues is achieved by a relatively small repertoire of basic morphogenetic events (e.g. cell adhesion, locomotion, apoptosis, etc.), permutated in various seque...

    Authors: Elise Cachat, Weijia Liu, Peter Hohenstein and Jamie A Davies

    Citation: Journal of Biological Engineering 2014 8:26

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  36. Content type: Research

    Genetic material extracted from in situ microbial communities has high promise as an indicator of biological system status. However, the challenge is to access genomic information from all organisms at the popula...

    Authors: Ju Seok Lee, Junghuei Chen, Russell Deaton and Jin-Woo Kim

    Citation: Journal of Biological Engineering 2014 8:25

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